|
KMID : 0356920080550040452
|
|
Korean Journal of Anesthesiology
2008 Volume.55 No. 4 p.452 ~ p.457
|
|
|
A comparison of the suppression of cough reflex by intravenous lidocaine and remifentanil prior to extubation of the endotracheal tube
|
|
Kang Dong-Hwa
Lee Kun-Moo
Lim Se-Hun
Lee Jeong-Han
Cheong Soon-Ho
Choe Young-Kyun
Kim Young-Jae
Kim Young-Whan
Choi Suk-Whan
Lee Sang-Eun
Shin Chee-Mahn
|
|
|
Abstract
|
|
|
Background: Cough reflex in response to extubation of the endotracheal tube is common; however, the effect of remifentanil on cough reflex is uncertain. Therefore, we evaluated the effect of lidocaine and remifentanil on cough reflex following extubation.
Methods: Forty adult patients scheduled to undergo elective surgery in two hours were enrolled in this study. All patients received a standard anesthetic protocol. Following surgery, the patients were randomly divided into two groups, Group L (n = 20), which received 1.5 mg/kg of 2% lidocaine intravenously, and Group R (n = 20), which received 0.5 ?g/kg remifentanil intravenously. Treatment was administered immediately after the patients opened their eyes, after which extubation was performed. We then evaluated breath holding and recorded the number of coughs at 5 minutes, 15 minutes and 30 minutes after extubation. In addition, we checked for sore throat 30 minutes after extubation.
Results: The number of coughs was significantly lower in Group R than in Group L at 5 minutes after extubation. However, there was no significant difference in the number of coughs in Group R and Group L at any other times evaluated.
Conclusions: There are no significant differences in suppression of the cough reflex in response to treatment with lidocaine and remifentanil
|
|
|
KEYWORD
|
|
|
cough relex, extubation, lidocaine, remifentanil
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|
|